How To Clean A Memory Foam Mattress With Urine. However do not use any bleach on the memory foam mattress. Absorb it place absorbent towels over the stain and press them into the mattress to absorb as much of the liquid as you can.

Mix the fabric cleaner and water together thoroughly before spraying it on your mattress. Vinegar also helps break down the uric acid found in urine making it easier to remove. Press down on the foam on the wet spot to distribute the liquid better into the foam for a more thorough cleaning.
Let the mattress dry.
Press down on the foam on the wet spot to distribute the liquid better into the foam for a more thorough cleaning. To remove any stains you can use bleach. Vinegar and baking soda are both powerhouse natural cleaners that help neutralize the ammonia smell of urine. Use a white sponge or rag dye from colored materials could transfer to the latex and stain to lightly blot the top of the mattress not rub which could tear the material.